Searchable abstracts of presentations at key conferences in endocrinology

ea0028p135 | Growth and development | SFEBES2012

Loss of annexin 1 in mice leads to reduced proliferation in the neurogenic subventricular zone

Stock Lisanne , Szele Francis , Morris John , Christian Helen

Annexin 1 (ANXA1) is a glucocorticoid-regulated, calcium and phospholipid-binding protein well recognized as an important signalling intermediate in both peripheral systems and the brain. Online adult mouse brain gene libraries have reported ANXA1 mRNA expression in the subventricular zone (SVZ) lining the lateral ventricles. The SVZ is one of the two largest neurogenic areas of the brain and as ANXA1 plays a known role in cell differentiation and proliferation, we have invest...